Combine. Place the white vinegar in a glass measuring cup. Add enough milk to make 2 cups total.
Rest. Stir and then let the mixture stand for 15 minutes. The milk will begin to curdle.
Enjoy! Use your homemade buttermilk right away, or cover and refrigerate.
Notes
This substitute does mimic the function of buttermilk, however, it does lack the classic buttermilk flavor. This is a great substitute when a recipe calls for buttermilk, but you don't have any on hand.