Heat olive oil over medium-high heat in a large nonstick skillet or a dutch oven.
Add onions and cook for 3 minutes.
Stir in garlic and cook for 1 minute.
Add ground turkey and season with, chili powder, paprika, salt and pepper and cook for 4 to 5 minutes, stirring occasionally, until meat is browned; remove from heat and drain out the liquid.
Add pasta, cheese, flour, milk, chicken broth and worcestershire sauce to the prepared meat; stir to combine.
Bring mixture to a boil, stirring frequently; lower to a simmer and cover with a lid.
Continue to cook for 8 to 10 minutes, stirring frequently, until pasta is thoroughly cooked.
Remove from heat and taste for seasonings; adjust accordingly.
Serve.